Scientific articles:

I'm a nerd, so I actually enjoy doing research to become more knowledgeable, and these are my favorite articles: (All links open in a new tab)

4/28/14:

Interesting article, but I remember seeing a different one that points to a spot between the frontal sinus and the nasal concha as the receptor site for Ketamine. My own personal experience: aim for whatever makes your brain say *ooof, that's the spot! *

https://www.intechopen.com/books/drug-discovery-and-development-from-molecules-to-medicine/intranasal-drug-administration-an-attractive-delivery-route-for-some-drugs

3/28/19:

Researchers at the University of Maryland School of Medicine (UMSOM) have discovered a crucial receptor called mGlu2 that is critical to the mechanism of fast-acting antidepressants such as ketamine when used to treat depression

https://medicalxpress.com/news/2019-03-critical-receptor-involved-response-antidepressants.html

4/11/19:

Chronic stress seems to be mitigated in mouse models. I can absolutely attest that my stress level after a good session is greatly reduced. It's like my energy bucket is full again.

https://www.statnews.com/2019/04/11/research-ketamine-antidepressant-effect/

11/18/19:

Fighting alcoholism with Ketamine. I can attest to my decreased desire to drink. I've lost quite a bit more weight without the need to get buzzed every night.

https://www.inverse.com/article/61006-potential-ketamine-treatment-for-alcohol-abuse-disorder

5/31/2020:

Tracers find that ketamine increases dopamine, and decreases serotonin. Finally the link to ssri.

https://newatlas.com/medical/serotonin-ketamine-antidepressant-new-mechanism-discovery-imaging-study

3/28/17:

Ketamine for the treatment of major depressive disorder and bipolar depression: A review of the literature.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007654/